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Methyl-Beta-Cyclodextrin Restores K(IR) Channel Function in Brain Endothelium of Female Alzheimer’s Disease Mice

BACKGROUND: As the sixth-leading cause of death in the United States, Alzheimer’s disease (AD) entails deteriorating endothelial control of blood flow throughout the brain. In particular, reduced inward-rectifying K(+) (K(IR)) channel function in animal models of aging and AD compromises endothelial...

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Detalles Bibliográficos
Autores principales: Hakim, Md A., Behringer, Erik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543374/
https://www.ncbi.nlm.nih.gov/pubmed/34755043
http://dx.doi.org/10.3233/ADR-210016