High p16(INK4a), a marker of cellular senescence, is associated with renal injury, impairment and outcome in lupus nephritis

OBJECTIVES: Because a significant fraction of patients with lupus nephritis (LN) develops renal impairment, there is a need to better understand the mechanisms underlying disease progression. Here, we assessed for cellular senescence in the LN kidney, and its association with disease severity and ou...

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Detalles Bibliográficos
Autores principales: Tilman, Gaëlle, Bouzin, Caroline, Aydin, Selda, Tamirou, Farah, Galant, Christine, Coulie, Pierre G, Houssiau, Frédéric, Lauwerys, Bernard, Limaye, Nisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Lupus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543753/
https://www.ncbi.nlm.nih.gov/pubmed/34686545
http://dx.doi.org/10.1136/rmdopen-2021-001844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543753/
https://www.ncbi.nlm.nih.gov/pubmed/34686545
http://dx.doi.org/10.1136/rmdopen-2021-001844

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