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High p16(INK4a), a marker of cellular senescence, is associated with renal injury, impairment and outcome in lupus nephritis

OBJECTIVES: Because a significant fraction of patients with lupus nephritis (LN) develops renal impairment, there is a need to better understand the mechanisms underlying disease progression. Here, we assessed for cellular senescence in the LN kidney, and its association with disease severity and ou...

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Detalles Bibliográficos
Autores principales:	Tilman, Gaëlle, Bouzin, Caroline, Aydin, Selda, Tamirou, Farah, Galant, Christine, Coulie, Pierre G, Houssiau, Frédéric, Lauwerys, Bernard, Limaye, Nisha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Lupus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543753/ https://www.ncbi.nlm.nih.gov/pubmed/34686545 http://dx.doi.org/10.1136/rmdopen-2021-001844

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