Application of the 3′ mRNA-Seq using unique molecular identifiers in highly degraded RNA derived from formalin-fixed, paraffin-embedded tissue

BACKGROUND: Archival formalin-fixed, paraffin-embedded (FFPE) tissue samples with clinical and histological data are a singularly valuable resource for developing new molecular biomarkers. However, transcriptome analysis remains challenging with standard mRNA-seq methods as FFPE derived-RNA samples...

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Detalles Bibliográficos
Autores principales: Jang, Jin Sung, Holicky, Eileen, Lau, Julie, McDonough, Samantha, Mutawe, Mark, Koster, Matthew J., Warrington, Kenneth J., Cuninngham, Julie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543821/
https://www.ncbi.nlm.nih.gov/pubmed/34689749
http://dx.doi.org/10.1186/s12864-021-08068-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543821/
https://www.ncbi.nlm.nih.gov/pubmed/34689749
http://dx.doi.org/10.1186/s12864-021-08068-1

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