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TPSC: a module detection method based on topology potential and spectral clustering in weighted networks and its application in gene co-expression module discovery

BACKGROUND: Gene co-expression networks are widely studied in the biomedical field, with algorithms such as WGCNA and lmQCM having been developed to detect co-expressed modules. However, these algorithms have limitations such as insufficient granularity and unbalanced module size, which prevent full...

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Detalles Bibliográficos
Autores principales: Liu, Yusong, Ye, Xiufen, Yu, Christina Y., Shao, Wei, Hou, Jie, Feng, Weixing, Zhang, Jie, Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543836/
https://www.ncbi.nlm.nih.gov/pubmed/34689740
http://dx.doi.org/10.1186/s12859-021-03964-5