Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers

BACKGROUND: 5-Hydroxymethylcytosine (5hmC) is a significant DNA epigenetic modification. However, the 5hmC modification alterations in genomic regions encoding long non-coding RNA (lncRNA) and their clinical significance remain poorly characterized. RESULTS: A three-phase discovery–modeling–validati...

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Detalles Bibliográficos
Autores principales: Zhou, Meng, Hou, Ping, Yan, Congcong, Chen, Lu, Li, Ke, Wang, Yiran, Zhao, Jingting, Su, Jianzhong, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543867/
https://www.ncbi.nlm.nih.gov/pubmed/34689838
http://dx.doi.org/10.1186/s13148-021-01183-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543867/
https://www.ncbi.nlm.nih.gov/pubmed/34689838
http://dx.doi.org/10.1186/s13148-021-01183-6

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