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19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway

BACKGROUND: Bufadienolides derived from the skin of toads are often regarded as the main active components with antitumor effects. 19-Hydroxybufalin (19-HB) is a monomer of bufadienolides; however, its effects and underlying molecular mechanisms on tumor growth remain to be ascertained. In this repo...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Zhang, Xiao, Zhang, Wei, Xiong, Minggang, Lin, Yuhan, Chang, Ming, Xu, Lin, Lu, Yi, Liu, Yun, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543904/
https://www.ncbi.nlm.nih.gov/pubmed/34696818
http://dx.doi.org/10.1186/s40164-021-00243-0