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Synchronous Rectal Tumours with Different Molecular and Genetic Phenotypes Occurring in a Patient with Lynch Syndrome

The increasingly widespread use of immunohistochemistry and next-generation sequencing (NGS) in the detection of microsatellite instability (MSI) and DNA mismatch repair (MMR) status has led to the observation of various unusual tumour types that exhibit MMR protein deficiency in Lynch syndrome (LS)...

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Detalles Bibliográficos
Autores principales: Gou, Qiheng, Xie, Yuxin, Zhang, Mengni, Chen, Ye, Shen, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544124/
https://www.ncbi.nlm.nih.gov/pubmed/34707409
http://dx.doi.org/10.2147/CMAR.S333690