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Activation of Microbiota Sensing – Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis

Multiple emerging evidence indicates that the gut microbiota contributes to the pathology of Alzheimer’s disease (AD)—a debilitating public health problem in older adults. However, strategies to beneficially modulate gut microbiota and its sensing signaling pathways remain largely unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Razazan, Atefeh, Karunakar, Prashantha, Mishra, Sidharth P., Sharma, Shailesh, Miller, Brandi, Jain, Shalini, Yadav, Hariom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544178/
https://www.ncbi.nlm.nih.gov/pubmed/34707491
http://dx.doi.org/10.3389/fnagi.2021.735933