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Activation of Microbiota Sensing – Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis
Multiple emerging evidence indicates that the gut microbiota contributes to the pathology of Alzheimer’s disease (AD)—a debilitating public health problem in older adults. However, strategies to beneficially modulate gut microbiota and its sensing signaling pathways remain largely unknown. Here, we...
Autores principales: | Razazan, Atefeh, Karunakar, Prashantha, Mishra, Sidharth P., Sharma, Shailesh, Miller, Brandi, Jain, Shalini, Yadav, Hariom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544178/ https://www.ncbi.nlm.nih.gov/pubmed/34707491 http://dx.doi.org/10.3389/fnagi.2021.735933 |
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