Expression and Display of Glycoengineered Antibodies and Antibody Fragments with an Engineered Yeast Strain

Interactions with cell surface receptors enhance the therapeutic properties of many important antibodies, including the low-affinity Fc γ Receptors (FcγRs). These interactions require proper processing of the immunoglobulin G Fc N-glycan, and eliminating the N-glycan abolishes binding, restricting a...

Descripción completa

Detalles Bibliográficos
Autores principales: Shenoy, Anjali, Yalamanchili, Srisaimaneesh, Davis, Alexander R., Barb, Adam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544235/
https://www.ncbi.nlm.nih.gov/pubmed/34698072
http://dx.doi.org/10.3390/antib10040038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544235/
https://www.ncbi.nlm.nih.gov/pubmed/34698072
http://dx.doi.org/10.3390/antib10040038

Ejemplares similares