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Expression and Display of Glycoengineered Antibodies and Antibody Fragments with an Engineered Yeast Strain
Interactions with cell surface receptors enhance the therapeutic properties of many important antibodies, including the low-affinity Fc γ Receptors (FcγRs). These interactions require proper processing of the immunoglobulin G Fc N-glycan, and eliminating the N-glycan abolishes binding, restricting a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544235/ https://www.ncbi.nlm.nih.gov/pubmed/34698072 http://dx.doi.org/10.3390/antib10040038 |