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Identification of hub genes and key pathways of paraquat-induced human embryonic pulmonary fibrosis by bioinformatics analysis and in vitro studies

Objective: Paraquat (N,N0-dimethyl-4,40-bipyridinium dichloride;PQ) is a highly toxic pesticide, which usually leads to acute lung injury and subsequent development of pulmonary fibrosis. The exact mechanism underlying PQ-induced lung fibrosis remain largely unclear and as yet, no specific treatment...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangxia, Hu, Jinlun, Yan, Mei, Xie, Chunming, Xu, Weigan, Hu, Qiaohua, Feng, Jinxia, Gu, Zi Cong, Fu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544307/
https://www.ncbi.nlm.nih.gov/pubmed/34580234
http://dx.doi.org/10.18632/aging.203570