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Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Locally recurrent rectal cancer (LRRC) leads to a poor prognosis and appears as a clinically predominant pattern of failure. In this research, whole-exome sequencing (WES) was performed on 21 samples from 8 patients to search for the molecular mechanisms of LRRC. The data was analyzed by bioinformat...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Gu, Xiaodong, Li, Zhenyang, Zheng, Chuang, Wang, Zihao, Zhou, Minwei, Chen, Zongyou, Li, Mengzhen, Li, Dongbing, Xiang, Jianbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544332/
https://www.ncbi.nlm.nih.gov/pubmed/34642262
http://dx.doi.org/10.18632/aging.203618