Cargando…

Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Locally recurrent rectal cancer (LRRC) leads to a poor prognosis and appears as a clinically predominant pattern of failure. In this research, whole-exome sequencing (WES) was performed on 21 samples from 8 patients to search for the molecular mechanisms of LRRC. The data was analyzed by bioinformat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yi, Gu, Xiaodong, Li, Zhenyang, Zheng, Chuang, Wang, Zihao, Zhou, Minwei, Chen, Zongyou, Li, Mengzhen, Li, Dongbing, Xiang, Jianbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544332/ https://www.ncbi.nlm.nih.gov/pubmed/34642262 http://dx.doi.org/10.18632/aging.203618

Ejemplares similares

Construction and validation of a prognostic nomogram for locally recurrent rectal cancer: a population-based study
por: Huang, Xiao, et al.
Publicado: (2023)

Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review)
por: CAI, YANTAO, et al.
Publicado: (2014)

Gallbladder carcinosarcoma accompanied with bile duct tumor thrombi: A case report
por: WANG, YAN, et al.
Publicado: (2013)

Whole-exome sequencing of rectal neuroendocrine tumors
por: Li, Yuanliang, et al.
Publicado: (2023)

Whole-exome sequencing identified recurrent and novel variants in benzene-induced leukemia
por: Lin, Dafeng, et al.
Publicado: (2023)

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
por: Wang, Jun, et al.
Publicado: (2021)

Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing
por: Wu, Song, et al.
Publicado: (2015)

Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy
por: CAI, YANTAO, et al.
Publicado: (2013)

Identification of a mature cystic teratoma mimicking a presacral tumor by transsacral surgery in a young female: A case report
por: YANG, YI, et al.
Publicado: (2013)

Fever of unknown origin as a presentation of colonic inflammatory myofibroblastic tumor in a 36-year-old female: A case report
por: ZHOU, RU, et al.
Publicado: (2014)

Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis
por: Zuo, Xianbo, et al.
Publicado: (2015)

Whole-exome Sequencing of Prostate Cancer in Sardinian Identify Recurrent UDP-glucuronosyltransferase Amplifications
por: Zeng, Tiansheng, et al.
Publicado: (2021)

Whole exome sequencing in unexplained recurrent miscarriage families identified novel pathogenic genetic causes of euploid miscarriage
por: Wang, Xiyao, et al.
Publicado: (2023)

Mesenteric lymphatic hygroma in adults: A case report with a review of the literature
por: YANG, YI, et al.
Publicado: (2014)

Exome and whole genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
por: Dulak, Austin M., et al.
Publicado: (2013)

Author Correction: Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis
por: Zuo, Xianbo, et al.
Publicado: (2018)

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma
por: Wong, Stephen Q., et al.
Publicado: (2014)

Common Variable Immunodeficiency with Genetic Defects Identified by Whole Exome Sequencing
por: Li, Ran, et al.
Publicado: (2018)

Whole Exome Sequencing Identifies Genes Associated With Non-Obstructive Azoospermia
por: Zhang, Hongguo, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress-Mediated Apoptosis Involved in Indirect Recognition Pathway Blockade Induces Long-Term Heart Allograft Survival
por: Xiang, Jianbin, et al.
Publicado: (2010)

Myeloid-Derived Suppressor Cells Participate in Preventing Graft Rejection
por: Wang, Yan, et al.
Publicado: (2012)

MicroRNA-155 acts as a tumor suppressor in colorectal cancer by targeting CTHRC1 in vitro
por: Liu, Jingtian, et al.
Publicado: (2018)

Whole Exome Sequencing Identifies Novel Recurrently Mutated Genes in Patients with Splenic Marginal Zone Lymphoma
por: Parry, Marina, et al.
Publicado: (2013)

Pathogenic variants identified by whole-exome sequencing in 43 patients with epilepsy
por: Zhang, Linlin, et al.
Publicado: (2020)

Identification of genetic polymorphisms in unexplained recurrent spontaneous abortion based on whole exome sequencing
por: Mou, Jiang-Tao, et al.
Publicado: (2022)

Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases
por: Wang, Linlin, et al.
Publicado: (2019)

Whole exome sequencing identifies common mutational landscape of cervix and endometrium small cell neuroendocrine carcinoma
por: Wang, Wei, et al.
Publicado: (2023)

Whole exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas
por: Fishbein, Lauren, et al.
Publicado: (2015)

Potential digenic inheritance of familial hypertrophic cardiomyopathy identified by whole‐exome sequencing
por: Ren, Ming‐Bao, et al.
Publicado: (2020)

Novel rare genetic variants of familial and sporadic pulmonary atresia identified by whole-exome sequencing
por: Xing, Junyue, et al.
Publicado: (2023)

Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors
por: Chmielecki, Juliann, et al.
Publicado: (2013)

Whole-exome sequencing identifies variants in invasive pituitary adenomas
por: Lan, Xiaolei, et al.
Publicado: (2016)

Whole-exome analysis in osteosarcoma to identify a personalized therapy
por: Chiappetta, Caterina, et al.
Publicado: (2017)

Whole exome sequencing identifies mutational signatures of vitreoretinal lymphoma
por: Lee, Junwon, et al.
Publicado: (2020)

Mendelian etiologies identified with whole exome sequencing in cerebral palsy
por: Chopra, Maya, et al.
Publicado: (2022)

Whole-exome sequencing identifies somatic mutations associated with lung cancer metastasis to the brain
por: Liu, Zhenghao, et al.
Publicado: (2021)

Endoscopic Thyroidectomy for Differentiated Thyroid Cancer
por: Yang, Yi, et al.
Publicado: (2012)

Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing
por: Lyu, Nan, et al.
Publicado: (2016)

Identification of Locally Advanced Rectal Cancer with Low Risk of Local Recurrence
por: Wang, Qiao-Xuan, et al.
Publicado: (2015)

Whole exome sequencing reveals the genetic heterogeneity and evolutionary history of primary gliomas and matched recurrences
por: Xu, Peng-Fei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_64utc90r0h80dgtikoqclkpdan