Patient Heterogeneity in Acute Myeloid Leukemia: Leukemic Cell Communication by Release of Soluble Mediators and Its Effects on Mesenchymal Stem Cells

Acute myeloid leukemia (AML) is an aggressive bone marrow malignancy, and non-leukemic stromal cells (including mesenchymal stem cells, MSCs) are involved in leukemogenesis and show AML-supporting effects. We investigated how constitutive extracellular mediator release by primary human AML cells alt...

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Detalles Bibliográficos
Autores principales: Aasebø, Elise, Brenner, Annette K., Hernandez-Valladares, Maria, Birkeland, Even, Mjaavatten, Olav, Reikvam, Håkon, Selheim, Frode, Berven, Frode S., Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544451/
https://www.ncbi.nlm.nih.gov/pubmed/34698165
http://dx.doi.org/10.3390/diseases9040074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544451/
https://www.ncbi.nlm.nih.gov/pubmed/34698165
http://dx.doi.org/10.3390/diseases9040074

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