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A genetically encoded sensor for measuring serotonin dynamics

Serotonin (5-HT) is a phylogenetically conserved monoamine neurotransmitter modulating important processes in the brain. To directly visualize the release of 5-HT, we developed a genetically encoded GPCR-Activation-Based 5-HT (GRAB(5-HT)) sensor with high sensitivity, selectivity, subsecond kinetics...

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Detalles Bibliográficos
Autores principales: Wan, Jinxia, Peng, Wanling, Li, Xuelin, Qian, Tongrui, Song, Kun, Zeng, Jianzhi, Deng, Fei, Hao, Suyu, Feng, Jiesi, Zhang, Peng, Zhang, Yajun, Zou, Jing, Pan, Sunlei, Shin, Mimi, Venton, B. Jill, Zhu, J. Julius, Jing, Miao, Xu, Min, Li, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544647/
https://www.ncbi.nlm.nih.gov/pubmed/33821000
http://dx.doi.org/10.1038/s41593-021-00823-7