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Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains

The Trypanosoma brucei repeat (TBR) is a tandem repeat sequence present on the Trypanozoon minichromosomes. Here, we report that the TBR sequence is not as homogenous as previously believed. BLAST analysis of the available T. brucei genomes reveals various TBR sequences of 177 bp and 176 bp in lengt...

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Detalles Bibliográficos
Autores principales: Van Reet, Nick, Patient Pyana, Pati, Dehou, Sara, Bebronne, Nicolas, Deborggraeve, Stijn, Büscher, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544829/
https://www.ncbi.nlm.nih.gov/pubmed/34695154
http://dx.doi.org/10.1371/journal.pone.0258711