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Expression profile of tumour suppressor protein p53 and its regulator MDM2 in a cohort of breast cancer patients in a Tertiary Hospital in Ghana

BACKGROUND: Inactivation or mutation of the tumour suppressor gene p53 or its regulator mouse double minute 2 (MDM2) is the commonest event in breast cancer. These altered genes usually express abnormally high levels of their proteins in many carcinomas. The phenotypic expression of p53 and MDM2 in...

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Detalles Bibliográficos
Autores principales: Opoku, Francis, Bedu-Addo, Kweku, Titiloye, Nicholas Akinwale, Atta Manu, Elijah, Ameh-Mensah, Charity, Duduyemi, Babatunde Moses
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544835/
https://www.ncbi.nlm.nih.gov/pubmed/34695137
http://dx.doi.org/10.1371/journal.pone.0258543