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Expression profile of tumour suppressor protein p53 and its regulator MDM2 in a cohort of breast cancer patients in a Tertiary Hospital in Ghana
BACKGROUND: Inactivation or mutation of the tumour suppressor gene p53 or its regulator mouse double minute 2 (MDM2) is the commonest event in breast cancer. These altered genes usually express abnormally high levels of their proteins in many carcinomas. The phenotypic expression of p53 and MDM2 in...
Autores principales: | Opoku, Francis, Bedu-Addo, Kweku, Titiloye, Nicholas Akinwale, Atta Manu, Elijah, Ameh-Mensah, Charity, Duduyemi, Babatunde Moses |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544835/ https://www.ncbi.nlm.nih.gov/pubmed/34695137 http://dx.doi.org/10.1371/journal.pone.0258543 |
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