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Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation

Plasmids play an important role in bacterial genome evolution by transferring genes between lineages. Fitness costs associated with plasmid carriage are expected to be a barrier to gene exchange, but the causes of plasmid fitness costs are poorly understood. Single compensatory mutations are often s...

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Detalles Bibliográficos
Autores principales: Hall, James P. J., Wright, Rosanna C. T., Harrison, Ellie, Muddiman, Katie J., Wood, A. Jamie, Paterson, Steve, Brockhurst, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544851/
https://www.ncbi.nlm.nih.gov/pubmed/34644303
http://dx.doi.org/10.1371/journal.pbio.3001225