Transcription Repressor Protein ZBTB25 Associates with HDAC1-Sin3a Complex in Mycobacterium tuberculosis-Infected Macrophages, and Its Inhibition Clears Pathogen by Autophagy

Downregulation of host gene expression is a key strategy employed by intracellular pathogens for their survival in macrophages and subsequent pathogenesis. In a previous study, we have shown that histone deacetylase 1 (HDAC1) levels go up in macrophages infected with Mycobacterium tuberculosis, and...

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Detalles Bibliográficos
Autores principales: Madhavan, Aravind, Arun, K. B., Pushparajan, Akhil Raj, Balaji, M., Kumar, Ramakrishnan Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544881/
https://www.ncbi.nlm.nih.gov/pubmed/33627504
http://dx.doi.org/10.1128/mSphere.00036-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544881/
https://www.ncbi.nlm.nih.gov/pubmed/33627504
http://dx.doi.org/10.1128/mSphere.00036-21

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