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Identification and Characterization of Novel Antibody Epitopes on the N2 Neuraminidase

The influenza virus neuraminidase (NA) is becoming a focus for novel vaccine designs. However, the epitopes of human anti-NA antibodies have been poorly defined. Using a panel of 10 anti-N2 monoclonal antibodies (MAbs) that bind the H3N2 virus A/Switzerland/9715293/2013, we generated five escape mut...

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Detalles Bibliográficos
Autores principales: Kirkpatrick Roubidoux, Ericka, McMahon, Meagan, Carreño, Juan Manuel, Capuano, Christina, Jiang, Kaijun, Simon, Viviana, van Bakel, Harm, Wilson, Patrick, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544889/
https://www.ncbi.nlm.nih.gov/pubmed/33568453
http://dx.doi.org/10.1128/mSphere.00958-20