Engineering a Cysteine-Deficient Functional Candida albicans Cdr1 Molecule Reveals a Conserved Region at the Cytosolic Apex of ABCG Transporters Important for Correct Folding and Trafficking of Cdr1

Pleiotropic drug resistance (PDR) ATP-binding cassette (ABC) transporters of the ABCG family are eukaryotic membrane proteins that pump an array of compounds across organelle and cell membranes. Overexpression of the archetype fungal PDR transporter Cdr1 is a major cause of azole antifungal drug res...

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Detalles Bibliográficos
Autores principales: Madani, Golnoush, Lamping, Erwin, Cannon, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544900/
https://www.ncbi.nlm.nih.gov/pubmed/33568458
http://dx.doi.org/10.1128/mSphere.01318-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544900/
https://www.ncbi.nlm.nih.gov/pubmed/33568458
http://dx.doi.org/10.1128/mSphere.01318-20

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