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Intranasal delivery of interleukin-4 attenuates chronic cognitive deficits via beneficial microglial responses in experimental traumatic brain injury

Traumatic brain injury (TBI) is commonly followed by long-term cognitive deficits that severely impact the quality of life in survivors. Recent studies suggest that microglial/macrophage (Mi/MΦ) polarization could have multidimensional impacts on post-TBI neurological outcomes. Here, we report that...

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Detalles Bibliográficos
Autores principales: Pu, Hongjian, Ma, Cheng, Zhao, Yongfang, Wang, Yangfan, Zhang, Wenting, Miao, Wanying, Yu, Fang, Hu, Xiaoming, Shi, Yejie, Leak, Rehana K, Hitchens, T Kevin, Dixon, C Edward, Bennett, Michael VL, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545055/
https://www.ncbi.nlm.nih.gov/pubmed/34259069
http://dx.doi.org/10.1177/0271678X211028680