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Mechanisms of Attenuation by Genetic Recoding of Viruses

The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations. Elucida...

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Detalles Bibliográficos
Autores principales: Gonçalves-Carneiro, Daniel, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545087/
https://www.ncbi.nlm.nih.gov/pubmed/33402534
http://dx.doi.org/10.1128/mBio.02238-20