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Mechanisms of Attenuation by Genetic Recoding of Viruses
The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations. Elucida...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545087/ https://www.ncbi.nlm.nih.gov/pubmed/33402534 http://dx.doi.org/10.1128/mBio.02238-20 |