Cargando…
Mechanisms of Attenuation by Genetic Recoding of Viruses
The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations. Elucida...
Autores principales: | Gonçalves-Carneiro, Daniel, Bieniasz, Paul D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545087/ https://www.ncbi.nlm.nih.gov/pubmed/33402534 http://dx.doi.org/10.1128/mBio.02238-20 |
Ejemplares similares
-
Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding
por: Le Nouën, Cyril, et al.
Publicado: (2019) -
Attenuation of Viruses by Large-Scale Recoding of their Genomes: the Selection Is Always Biased
por: Osterrieder, Nikolaus, et al.
Publicado: (2018) -
Current status of the genetic susceptibility in attenuated adenomatous polyposis
por: Lorca, Víctor, et al.
Publicado: (2019) -
Rational attenuation of RNA viruses with zinc finger antiviral protein
por: Gonçalves-Carneiro, Daniel, et al.
Publicado: (2022) -
Drosophila as a genetic model for studying pathogenic human viruses
por: Hughes, Tamara T., et al.
Publicado: (2012)