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Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates

Invasive bacterial infections during pregnancy are a major risk factor for preterm birth, stillbirth, and fetal injury. Group B streptococci (GBS) are Gram-positive bacteria that asymptomatically colonize the lower genital tract but infect the amniotic fluid and induce preterm birth or stillbirth. E...

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Detalles Bibliográficos
Autores principales: Coleman, Michelle, Armistead, Blair, Orvis, Austyn, Quach, Phoenicia, Brokaw, Alyssa, Gendrin, Claire, Sharma, Kavita, Ogle, Jason, Merillat, Sean, Dacanay, Matthew, Wu, Tsung-Yen, Munson, Jeff, Baldessari, Audrey, Vornhagen, Jay, Furuta, Anna, Nguyen, Shayla, Adams Waldorf, Kristina M., Rajagopal, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545101/
https://www.ncbi.nlm.nih.gov/pubmed/33402537
http://dx.doi.org/10.1128/mBio.03115-20