A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion

Genomic surveillance of viral isolates during the 2013–2016 Ebola virus epidemic in Western Africa, the largest and most devastating filovirus outbreak on record, revealed several novel mutations. The responsible strain, named Makona, carries an A-to-V substitution at position 82 (A82V) in the glyco...

Descripción completa

Detalles Bibliográficos
Autores principales: Fels, J. Maximilian, Bortz, Robert H., Alkutkar, Tanwee, Mittler, Eva, Jangra, Rohit K., Spence, Jennifer S., Chandran, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545129/
https://www.ncbi.nlm.nih.gov/pubmed/33593971
http://dx.doi.org/10.1128/mBio.03616-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545129/
https://www.ncbi.nlm.nih.gov/pubmed/33593971
http://dx.doi.org/10.1128/mBio.03616-20

Ejemplares similares