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Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates

Acinetobacter baumannii is a Gram-negative pathogen that has emerged as one of the most highly antibiotic-resistant bacteria worldwide. Multidrug efflux within these highly drug-resistant strains and other opportunistic pathogens is a major cause of failure of drug-based treatments of infectious dis...

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Detalles Bibliográficos
Autores principales: Morgan, Christopher E., Glaza, Przemyslaw, Leus, Inga V., Trinh, Anhthu, Su, Chih-Chia, Cui, Meng, Zgurskaya, Helen I., Yu, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545137/
https://www.ncbi.nlm.nih.gov/pubmed/33622726
http://dx.doi.org/10.1128/mBio.03690-20