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Clustering FunFams using sequence embeddings improves EC purity

MOTIVATION: Classifying proteins into functional families can improve our understanding of protein function and can allow transferring annotations within one family. For this, functional families need to be ‘pure’, i.e., contain only proteins with identical function. Functional Families (FunFams) cl...

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Detalles Bibliográficos
Autores principales: Littmann, Maria, Bordin, Nicola, Heinzinger, Michael, Schütze, Konstantin, Dallago, Christian, Orengo, Christine, Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545299/
https://www.ncbi.nlm.nih.gov/pubmed/33978744
http://dx.doi.org/10.1093/bioinformatics/btab371