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Highly active engineered IgG3 antibodies against SARS-CoV-2

Monoclonal antibodies (mAbs) that efficiently neutralize SARS-CoV-2 have been developed at an unprecedented speed. Notwithstanding, there is a vague understanding of the various Ab functions induced beyond antigen binding by the heavy-chain constant domain. To explore the diverse roles of Abs in SAR...

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Detalles Bibliográficos
Autores principales: Kallolimath, Somanath, Sun, Lin, Palt, Roman, Stiasny, Karin, Mayrhofer, Patrick, Gruber, Clemens, Kogelmann, Benjamin, Chen, Qiang, Steinkellner, Herta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545452/
https://www.ncbi.nlm.nih.gov/pubmed/34599091
http://dx.doi.org/10.1073/pnas.2107249118