The low-complexity domain of the FUS RNA binding protein self-assembles via the mutually exclusive use of two distinct cross-β cores

The low-complexity (LC) domain of the fused in sarcoma (FUS) RNA binding protein self-associates in a manner causing phase separation from an aqueous environment. Incubation of the FUS LC domain under physiologically normal conditions of salt and pH leads to rapid formation of liquid-like droplets t...

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Detalles Bibliográficos
Autores principales: Kato, Masato, McKnight, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545455/
https://www.ncbi.nlm.nih.gov/pubmed/34654750
http://dx.doi.org/10.1073/pnas.2114412118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545455/
https://www.ncbi.nlm.nih.gov/pubmed/34654750
http://dx.doi.org/10.1073/pnas.2114412118

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