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Synapse development is regulated by microglial THIK-1 K(+) channels

Microglia are the resident immune cells of the central nervous system. They constantly survey the brain parenchyma for redundant synapses, debris, or dying cells, which they remove through phagocytosis. Microglial ramification, motility, and cytokine release are regulated by tonically active THIK-1...

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Detalles Bibliográficos
Autores principales: Izquierdo, Pablo, Shiina, Hiroko, Hirunpattarasilp, Chanawee, Gillis, Grace, Attwell, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545484/
https://www.ncbi.nlm.nih.gov/pubmed/34642249
http://dx.doi.org/10.1073/pnas.2106294118