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Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

Trained immunity defines long-lasting adaptations of innate immunity based on transcriptional and epigenetic modifications of myeloid cells and their bone marrow progenitors [M. Divangahi et al., Nat. Immunol. 22, 2–6 (2021)]. Innate immune cells, however, do not exclusively differentiate between fo...

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Detalles Bibliográficos
Autores principales: Jentho, Elisa, Ruiz-Moreno, Cristian, Novakovic, Boris, Kourtzelis, Ioannis, Megchelenbrink, Wout. L., Martins, Rui, Chavakis, Triantafyllos, Soares, Miguel P., Kalafati, Lydia, Guerra, Joel, Roestel, Franziska, Bohm, Peter, Godmann, Maren, Grinenko, Tatyana, Eugster, Anne, Beretta, Martina, Joosten, Leo A. B., Netea, Mihai G., Bauer, Michael, Stunnenberg, Hendrik G., Weis, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545490/
https://www.ncbi.nlm.nih.gov/pubmed/34663697
http://dx.doi.org/10.1073/pnas.2102698118