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Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme
Trained immunity defines long-lasting adaptations of innate immunity based on transcriptional and epigenetic modifications of myeloid cells and their bone marrow progenitors [M. Divangahi et al., Nat. Immunol. 22, 2–6 (2021)]. Innate immune cells, however, do not exclusively differentiate between fo...
Autores principales: | Jentho, Elisa, Ruiz-Moreno, Cristian, Novakovic, Boris, Kourtzelis, Ioannis, Megchelenbrink, Wout. L., Martins, Rui, Chavakis, Triantafyllos, Soares, Miguel P., Kalafati, Lydia, Guerra, Joel, Roestel, Franziska, Bohm, Peter, Godmann, Maren, Grinenko, Tatyana, Eugster, Anne, Beretta, Martina, Joosten, Leo A. B., Netea, Mihai G., Bauer, Michael, Stunnenberg, Hendrik G., Weis, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545490/ https://www.ncbi.nlm.nih.gov/pubmed/34663697 http://dx.doi.org/10.1073/pnas.2102698118 |
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