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Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project

BACKGROUND: Adaptive designs offer great promise in improving the efficiency and patient-benefit of clinical trials. An important barrier to further increased use is a lack of understanding about which additional resources are required to conduct a high-quality adaptive clinical trial, compared to a...

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Detalles Bibliográficos
Autores principales: Wilson, Nina, Biggs, Katie, Bowden, Sarah, Brown, Julia, Dimairo, Munyaradzi, Flight, Laura, Hall, Jamie, Hockaday, Anna, Jaki, Thomas, Lowe, Rachel, Murphy, Caroline, Pallmann, Philip, Pilling, Mark A., Snowdon, Claire, Sydes, Matthew R., Villar, Sofía S., Weir, Christopher J., Welburn, Jessica, Yap, Christina, Maier, Rebecca, Hancock, Helen, Wason, James M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545558/
https://www.ncbi.nlm.nih.gov/pubmed/34696781
http://dx.doi.org/10.1186/s12916-021-02124-z