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Mechanisms of Hydroxyurea-Induced Cellular Senescence: An Oxidative Stress Connection?
Hydroxyurea (HU) is a water-soluble antiproliferative agent used for decades in neoplastic and nonneoplastic conditions. HU is considered an essential medicine because of its cytoreduction functions. HU is an antimetabolite that inhibits ribonucleotide reductase, which causes a depletion of the deox...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545575/ https://www.ncbi.nlm.nih.gov/pubmed/34707779 http://dx.doi.org/10.1155/2021/7753857 |