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Dose-dependent immunomodulatory effects of bortezomib in experimental autoimmune neuritis

Proteasome inhibition with bortezomib has been reported to exert an immunomodulatory action in chronic autoimmune neuropathies. However, bortezomib used for the treatment of multiple myeloma induces a painful toxic polyneuropathy at a higher concentration. Therefore, we addressed this controversial...

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Detalles Bibliográficos
Autores principales: Klimas, Rafael, Sgodzai, Melissa, Motte, Jeremias, Mohamad, Nuwin, Renk, Pia, Blusch, Alina, Grüter, Thomas, Pedreiturria, Xiomara, Gobrecht, Philipp, Fischer, Dietmar, Schneider-Gold, Christiane, Reinacher-Schick, Anke, Tannapfel, Andrea, Yoon, Min-Suk, Gold, Ralf, Pitarokoili, Kalliopi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545613/
https://www.ncbi.nlm.nih.gov/pubmed/34708206
http://dx.doi.org/10.1093/braincomms/fcab238