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Dose-dependent immunomodulatory effects of bortezomib in experimental autoimmune neuritis
Proteasome inhibition with bortezomib has been reported to exert an immunomodulatory action in chronic autoimmune neuropathies. However, bortezomib used for the treatment of multiple myeloma induces a painful toxic polyneuropathy at a higher concentration. Therefore, we addressed this controversial...
Autores principales: | Klimas, Rafael, Sgodzai, Melissa, Motte, Jeremias, Mohamad, Nuwin, Renk, Pia, Blusch, Alina, Grüter, Thomas, Pedreiturria, Xiomara, Gobrecht, Philipp, Fischer, Dietmar, Schneider-Gold, Christiane, Reinacher-Schick, Anke, Tannapfel, Andrea, Yoon, Min-Suk, Gold, Ralf, Pitarokoili, Kalliopi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545613/ https://www.ncbi.nlm.nih.gov/pubmed/34708206 http://dx.doi.org/10.1093/braincomms/fcab238 |
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