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An automated platform for structural analysis of membrane proteins through serial crystallography

Membrane proteins are central to many pathophysiological processes, yet remain very difficult to analyze structurally. Moreover, high-throughput structure-based drug discovery has not yet been exploited for membrane proteins because of lack of automation. Here, we present a facile and versatile plat...

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Detalles Bibliográficos
Autores principales: Healey, Robert D., Basu, Shibom, Humm, Anne-Sophie, Leyrat, Cedric, Cong, Xiaojing, Golebiowski, Jérôme, Dupeux, Florine, Pica, Andrea, Granier, Sébastien, Márquez, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545655/
https://www.ncbi.nlm.nih.gov/pubmed/34723237
http://dx.doi.org/10.1016/j.crmeth.2021.100102