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An automated platform for structural analysis of membrane proteins through serial crystallography
Membrane proteins are central to many pathophysiological processes, yet remain very difficult to analyze structurally. Moreover, high-throughput structure-based drug discovery has not yet been exploited for membrane proteins because of lack of automation. Here, we present a facile and versatile plat...
Autores principales: | Healey, Robert D., Basu, Shibom, Humm, Anne-Sophie, Leyrat, Cedric, Cong, Xiaojing, Golebiowski, Jérôme, Dupeux, Florine, Pica, Andrea, Granier, Sébastien, Márquez, José Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545655/ https://www.ncbi.nlm.nih.gov/pubmed/34723237 http://dx.doi.org/10.1016/j.crmeth.2021.100102 |
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