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A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions

Extant fold‐switching proteins remodel their secondary structures and change their functions in response to cellular stimuli, regulating biological processes and affecting human health. Despite their biological importance, these proteins remain understudied. Predictive methods are needed to expedite...

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Detalles Bibliográficos
Autores principales: Mishra, Soumya, Looger, Loren L., Porter, Lauren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545793/
https://www.ncbi.nlm.nih.gov/pubmed/34498740
http://dx.doi.org/10.1002/bip.23471