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A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions
Extant fold‐switching proteins remodel their secondary structures and change their functions in response to cellular stimuli, regulating biological processes and affecting human health. Despite their biological importance, these proteins remain understudied. Predictive methods are needed to expedite...
Autores principales: | Mishra, Soumya, Looger, Loren L., Porter, Lauren L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545793/ https://www.ncbi.nlm.nih.gov/pubmed/34498740 http://dx.doi.org/10.1002/bip.23471 |
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