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A Single Low Dose of Dexmedetomidine Efficiently Attenuates Esketamine-Induced Overactive Behaviors and Neuronal Hyperactivities in Mice

Introduction: Esketamine (Esk) (S(+)-ketamine) is now used as an alternative to its racemic mixture, i. e., ketamine in anesthesia. Esk demonstrated more powerful potency and rapid recovery in anesthesia and less psychotomimetic side effects comparing with ketamine, but Esk could still induce psycho...

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Detalles Bibliográficos
Autores principales: Chu, Qinjun, Zhu, Kuicheng, Bai, Yafan, Shang, Huijie, Zhang, Dongqing, Zhao, Mingming, Zheng, Ping, Jin, Xiaogao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545873/
https://www.ncbi.nlm.nih.gov/pubmed/34712126
http://dx.doi.org/10.3389/fnhum.2021.735569