LOX-1 Deletion Attenuates Myocardial Fibrosis in the Aged Mice, Particularly Those With Hypertension

Background: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a transmembrane glycoprotein that mediates uptake of oxidized low-density lipoprotein (ox-LDL) into cells. Previous studies had shown that LOX-1 deletion had a potential to inhibit cardiac fibrosis in mouse models of hype...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Tang, Xihe, Liu, Bo, Zhang, Jinghang, Zhang, Yongxi, Lv, Hefan, Liu, Dongling, Mehta, Jawahar L., Wang, Xianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545876/
https://www.ncbi.nlm.nih.gov/pubmed/34712709
http://dx.doi.org/10.3389/fcvm.2021.736215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545876/
https://www.ncbi.nlm.nih.gov/pubmed/34712709
http://dx.doi.org/10.3389/fcvm.2021.736215

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