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Role of fibulin-5 insufficiency and prolapse progression on murine vaginal biomechanical function

The vagina plays a critical role in supporting the pelvic organs and loss of support leads to pelvic organ prolapse. It is unknown what microstructural changes influence prolapse progression nor how decreased elastic fibers contributes to vaginal remodeling and smooth muscle contractility. The objec...

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Detalles Bibliográficos
Autores principales: Clark-Patterson, Gabrielle L., Roy, Sambit, Desrosiers, Laurephile, Knoepp, Leise R., Sen, Aritro, Miller, Kristin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546087/
https://www.ncbi.nlm.nih.gov/pubmed/34697337
http://dx.doi.org/10.1038/s41598-021-00351-1