Evaluation of Pirfenidone and Nintedanib in a Human Lung Model of Fibrogenesis

Introduction: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal lung disease with a poor prognosis and increasing incidence. Pirfenidone and nintedanib are the only approved treatments for IPF but have limited efficacy and their mechanisms of action are poorly understood. Here we have exam...

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Detalles Bibliográficos
Autores principales: Roach, KM, Castells, E, Dixon, K, Mason, S, Elliott, G, Marshall, H, Poblocka, MA, Macip, S, Richardson, M, Khalfaoui, L, Bradding, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546112/
https://www.ncbi.nlm.nih.gov/pubmed/34712131
http://dx.doi.org/10.3389/fphar.2021.679388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546112/
https://www.ncbi.nlm.nih.gov/pubmed/34712131
http://dx.doi.org/10.3389/fphar.2021.679388

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