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DNA Damage Repair Deficiency in Pancreatic Ductal Adenocarcinoma: Preclinical Models and Clinical Perspectives

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide, and survival rates have barely improved in decades. In the era of precision medicine, treatment strategies tailored to disease mutations have revolutionized cancer therapy. Next generation sequencing has found that...

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Detalles Bibliográficos
Autores principales: Stoof, Jojanneke, Harrold, Emily, Mariottino, Sarah, Lowery, Maeve A., Walsh, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546202/
https://www.ncbi.nlm.nih.gov/pubmed/34712667
http://dx.doi.org/10.3389/fcell.2021.749490